CHONDROSARCOMA OF THE PROXIMAL HUMERUS IN A STATE PHILANTHROPIC HOSPITAL
CHONDROSARCOMA (Português (Brasil))

Keywords

Bone neoplasms, chondrosarcoma, epidemiology

How to Cite

Henrique Campoy Guedes, V. ., Filgueira Leite, I. ., Carlos de Lacerda Leite, . J. ., Suely Queiroz Silva Ribeiro, K. ., Sobreira Camurça, R. ., Vasconcelos Vieira Siqueira, V. ., Alexandra Naranjo Espinoza, V. ., & Luís Lopes Gomes de Siqueira, A. . (2023). CHONDROSARCOMA OF THE PROXIMAL HUMERUS IN A STATE PHILANTHROPIC HOSPITAL. Health and Society, 3(01), 286–311. https://doi.org/10.51249/hs.v3i01.1177

Abstract

Objective: To analyze the clinical and epidemiological profile of patients with chondrosarcoma of the proximal humerus treated at a Philanthropic Hospital over a period of 5 years. Methods: Documentary, exploratory, descriptive study, conducted by 04 medical records of patients admitted to the Orthopedic Oncology service, with a diagnosis of chondrosarcoma located in the proximal humerus in the period 2014 to 2018. The sex, age, staging, radiology, and surgery performed were investigated. The data obtained were analyzed by descriptive statistics with the aid of the RStudio software. The study was approved by the Research Ethics Committee. Results: All patients were female, and the age ranged from 37 to 50 years. The most frequent symptom was mild local pain, there was no evidence of loss of function at the time of diagnosis. Radiology showed an expansive, lobulated lesion with intermingled calcification. Histology, two cases of grade I chondrosarcoma, one case grade II and one grade III. Enneking I staging 50% and Enneking II in 2 cases. Surgery ranged from local curettage to en bloc resection. Recurrence was null at follow-up time. Conclusion: It is a rare disease with a small number of cases, but it initiates an analysis for further studies in its epidemiology and treatment.

https://doi.org/10.51249/hs.v3i01.1177
CHONDROSARCOMA (Português (Brasil))

References

ALTAY, M.; BAYRAKCI, K.; YILDIZ, Y.; EREKUL, S.; SAGLIK, Y. Secondary chondrosarcoma in cartilage bone tumors: report of 32 patients. J Orthop Sci, v. 5, n. 12, p. 415-423, 2007.

ANGELINI, A.; GUERRA, G. MAVROGENIS, A.F.; PALA, E.; PICCI, P.; RUGGIERI, P. Clinical outcome of central conventional chondrosarcoma. J Surg Oncol, v. 8, n. 106, p. 929-937, 2012.

BJORNSSON, J.; MCLEOD, R.A.; UNNI, K.K.; ILSTRUP, D.M.; PRITCHARD, D.J. Primary chondrosarcoma of long bones and limb girdles. Cancer, v. 10, n. 83, p. 2105-2019, 1998.

BOVEE, J.V. Multiple osteochondromas. Orphanel J Rare Dis, v. 3, n. 3, 2008.

CAPANNA, R.; VAN HORN, R.; BIAGINI, R.; RUGGIERI, P.; FERRUZI, A.; CAMPANACCI, M. The Tikhoff-Linberg procedure for bone tumors of the proximal humerus: the classical “extensive” technique versus a modified “transglenoid” resection. Archives of Orthopaedic and Trauma Surgery, n. 2, v. 109, p. 63-67, 1990.

CHOW, W.A. Chondrosarcoma: biology, genetics, and epigenetics. F100Research, v. 7, 2018.

DECKERS, C.; SCHREUDER, B.H.W.; HANNINK, G.; DE ROOY, J.W.J.; VAN DER GEEST, I.C.M. Radiologic follow‐up of untreated enchondroma and atypical cartilaginous tumors in the long bones. J Surg Oncol, v. 8, n. 114, p. 987-991, 2016.

DONATI, D.; YIN, J.Q.; COLANGELI, M.; COLANGELI, S.; BELLA, C.D.; BACCHINI, P.; BERTONI, F. Clear cell chondrosarcoma of bone: long time follow-up of 18 cases. Arch Orthop Trauma Surg, v. 2, n, 128, p. 137-42, 2008.

ENNEKING, W.F. A system of staging musculoskeletal neoplasms. Clin Orthop Relat Res, v. 204, p. 9-24, 1986.

EVANS, H.L.; AYALA, A.G.; ROMSDAHL, M.M. Prognostic factors in chondrosarcoma of bone. A clinicopathologic analysis with emphasis on histologic grading. Cancer, v. 40, n. 2, p. 818-831, 1977.

FIORENZA, F.; ABUDU, A.; GRIMER, R.J.; CARTER, S.R.; TILLMAN, R.M.; AYOUB, K.; MANGHAM, D.C.; DAVIES, A.M. Risk factors for survival and local control in chondrosarcoma of bone. J Bone Joint Surg Br, v. 1, n. 84, p. 93-99, 2002.

GIUFFRIDA, A.Y.; BURGUENO, J.E.; KONIARIS, L.G.; GUTIERREZ, J.C.; DUNCAN, R.; SCULLY, S.P. Chondrosarcoma in the United States (1973 to 2003): an analysis of 2890 cases from the SEER database. J Bone Joint Surg Am, v. 5, n. 91, p. 1063-1072, 2009.

GRIMER, R.J.; GOSHEGER, G.; TAMINIAU, A.; BIAU, D.; MATEJOVSKY, Z.; KOLLENDER, Y.; SAN-JULIAN, M.; GJERLINZONI, F.; FERRARI, C. Dedifferentiated chondrosarcoma: prognostic factors and outcome from a European group. Eur J Cancer, v. 4, n. 43, p. 2060-2065, 2007.

GUEDES, A. Cômite de oncologia ortopédica. Sociedade Brasileira de ortopedia e traumatologia, São Paulo, 20 de fev. de 2019.

HICKEY, M.; FARROKHYAR, F.; DEHESHI, B.; TURCOTTE, R.; GHERT, M. A systematic review and meta-analysis of intralesional versus wide resection for intramedullary grade I chondrosarcoma of the extremities. Ann Surg Oncol, v. 6, n. 18, p. 1705-1709, 2011.

HOGENDOORN, P.C.W.; BOVEE, J.M.; NIELSEN, G.P. Chondrosarcoma (grades I-III), including primary and secondary variants and periosteal chondrosarcoma. In: World Health Organization classification of tumours of soft tissue and bone, 4. ed., Lyon: IARC, v. 5, 2013.

LE, A.; BALL, D.; PITMAN, A.; FOX, R.; KING, K. Chondrosarcoma of bone complicating Ollier’s disease: report of a favourable response to radiotherapy. Australas Radiol, v. 3, n. 47, p. 322-324, 2003.

LEDDY, L.R.; HOLMES, R.E. Chondrosarcoma of Bone. Cancer Treatment and Research, v. 162, p. 117-130, 2014.

LEERAPUN, T.; HUGATE, R.R.; INWARDS, C.Y.; SCULLY, S.P.; SIM, F.H. Surgical management of conventional grade I chondrosarcoma of long bones. Clin Orthop Relat Res, v. 463, p. 166-172, 2007.

LITTRELL, L.A.; WENGER, D.E.; WOLD, L.E.; BERTONI, F.; UNNI, K.K.; WHITE, L.M.; KANDEL, R.; SUNDARAM, M. Radiographic, CT, and MR imaging features of dedifferentiated chondrosarcomas: a retrospective review of 174 new cases. Radiographics, v. 5, n. 24, p. 1397-1409, 2004.

MALAWER, M.; WITTIG, J. C. Overview of Resecions around the Shoulder Girdle: Anatomy, Surgical Considerations and Classification. Musculoskeletal Cancer Surgery, v. 9, p. 179-202, 2001.

MURPHEY, M.D.; WALKER, E.A.; WILSON, A.J.; KRANSDORF, M.J.; TEMPLE, H.T.; GANNON, F.H. From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics, v. 5, n. 23, p. 1245-1278, 2003.

NORMAND, A.; CANNON, C.; LEWIS, V.; LIN, P.; YASKO, A. Curettage of biopsy-diagnosed grade 1 periacetabular chondrosarcoma. Clin Orthop, v. 5, n. 459, p. 146-149, 2007.

PRAAG, V.; RUETEN, A.; HO, V.; DIJKSTRA, P. Incidence, outcomes and prognosticfactors during 25 years of treatment of chondrosarcomas. Surgical oncology, v. 27, n. 3, p. 402-408, 2018.

WOLF, R.E.; ENNEKING, W.F. The staging and surgery of musculoskeletal neoplasms. Orthop Clin North Am, v. 3, n. 27, p. 473-481, 1996.

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Copyright (c) 2023 Victor Henrique Campoy Guedes, Iracema Filgueira Leite, José Carlos de Lacerda Leite, Kátia Suely Queiroz Silva Ribeiro, Rayssa Sobreira Camurça, Viviane Vasconcelos Vieira Siqueira, Verónica Alexandra Naranjo Espinoza, André Luís Lopes Gomes de Siqueira

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