Health and Society

THE INFLUENCE OF THE TOOTH BANK AT THE PETROLINA HEALTH COLLEGE IN PERNAMBUCO

Anne Caroline Ribeiro Lacerda — 2025-05-13

Introduction: The Human Teeth Bank institution plays an important role in understanding teeth as organs and in controlling the illegal trade of teeth in Dentistry schools. Considering that the loan of teeth is essential in the training of professionals and future dentists, this is an academic extension project of Faculdade Soberana, which aims to regulate, monitor, and ensure the loan of natural teeth to students and professors. Objectives: This work aims to analyze, through this study, the performance of the Human Teeth Bank of Vale do São Francisco and how it is given regarding the legality of the origin of the teeth correlated with the receipt, preparation, and distribution. Materials and methods: An experience report was made of the activities carried out by the project participants since its foundation in March 2022 to December 2023, in addition to a systematization of the work, discussing the processes and management based on literature. Results: It was possible to analyze that the extension project plays an important role in the relationship of integration between students, professors, and technicians in the activities developed. As a consequence, it assumes notoriety in the ethical and bioethical sphere by eliminating the illegal form of tooth trade and contributing to distribution in addition to meeting educational and clinical needs. Conclusion: It is essential that during the training of dentists, there is the dissemination of content about the functioning and ethical and legal requirements for the use of human teeth, thus being able to eliminate the illegal trade of organs and contribute to enriching academic studies and research.

AVULSION OF DECIDUOUS TEETH

Mariana Meira Soares — 2025-05-13

Introduction: Dental avulsion is defined as the complete displacement of the tooth out of the alveolus, resulting in rupture of the periodontal ligament and, in some cases, fractures of the alveolar bone. Reimplantation of avulsed deciduous teeth is widely contraindicated. This is because this process can generate additional trauma to the permanent successor, especially due to the possibility of intrusion or direct injury to the germ. Objective: To analyze the clinical implications and contraindications of the reinsertion of avulsed deciduous teeth, highlighting the risks of complications for the permanent successor teeth and the impact on child dental development. Methodology: To develop this integrative literature review, the Pubmed, Scielo and BVS databases were used. Articles published between 2014 and 2024, covering the Portuguese, Spanish and English languages, were selected. Results: After a thorough review, the final set of studies included a total of 16 articles, indicating that the replacement of deciduous teeth is directly associated with several complications in those that will erupt later. Among the main consequences, damage to the permanent tooth germ stands out, resulting in changes in its growth, color and root curvature. Although there are few studies on the subject, it is clear that these factors can cause misalignment and delay in the eruption of permanent teeth, emphasizing the contraindication of reinsertion of the element. Conclusion: Tooth avulsion affects not only oral health, but also the aesthetics and quality of life of these patients. In these cases, the role of the dentist is essential, both to safely replant the tooth and to guide parents and guardians on the necessary care. Trauma to deciduous teeth can have a direct impact on the growth of permanent teeth, and specialized care, combined with prevention, helps to reduce the risk of sequelae that can affect the child throughout life.

THE ROLE OF THE DENTIST IN CARING FOR PATIENTS WITH Cleft Lip and Palate

Beatriz Durando Rebouças — 2025-05-13

Introduction: Cleft lip and palate are innate deformities in the anatomical fusion of facial processes. Objective: This literature review aims to highlight the relevance of the team of health professionals in providing a better quality of life to the patient. Methodology: The databases used were Pubmed and SciElo, in English, Portuguese and Spanish. Fifty-six articles were analyzed, of which only 13 met the inclusion criteria. Results: Since it is an opening in the lip and/or palate region, with multifactorial etiology presenting several consequences, dental follow-up is guided by the complexity of the cases. Conclusion: The dentist plays an essential role throughout the patient’s life, acting in both therapeutic and preventive ways, ensuring a comprehensive approach that includes functional, emotional and social aspects. Integration among health professionals is essential for effective rehabilitation and for improving the quality of life of these patients.

INFLUENCE OF ANALGESIC THERAPY ON THE AMPLIFICATION OF OROFACIAL PAIN

Daniel Dias Machado — 2025-05-13

This study addresses the influence of analgesic therapy on the amplification of orofacial pain, focusing on the pathophysiological mechanisms involving central sensitization and hyperalgesia in patients with chronic pain. Prolonged administration of analgesics, especially opioids, has been associated with the development of central sensitization, a process in which the central nervous system becomes more sensitive to painful stimuli, making pain more intense and harder to treat. Moreover, the continuous use of these medications can alter pain signaling pathways, such as the activation of NMDA receptors and the release of excitatory neurotransmitters, contributing to pain exacerbation. The impact of psychosocial comorbidities, such as anxiety and depression, was also analyzed, as these conditions can potentiate pain amplification, further complicating the management of orofacial pain. The study proposes the need for alternative or complementary therapeutic strategies, such as acupuncture and cognitive-behavioral therapy, to minimize the adverse effects of analgesic therapy and promote a more effective and safe treatment. A critical analysis of these mechanisms and the search for individualized approaches are essential for more efficient management of chronic orofacial pain.

EFFICACY, TOLERABILITY AND SAFETY OF CANNABIS OIL IN CHILDREN WITH AUTISM

Carolina Sousa Martins — 2025-05-23

Autism Spectrum Disorder is a neurological condition that presents itself in diverse ways, mainly affecting communication and behavior. Given the heterogeneity and particularity of each case, the search for appropriate treatment still becomes a great challenge. In this scenario, the use of Cannabis sativa oil has been noted as a potential alternative treatment. This literature review study aims to assess the clinical experience with the use of full-spectrum Cannabis sativa oil, rich in cannabidiol, in the treatment of people diagnosed with autism spectrum disorder. The objective of the study was to investigate aspects of tolerability, safety and possible therapeutic effects, in addition to highlighting the importance of individualized strategies in the management of this population. This research is a narrative literature review with an integrative approach, with the objective of gathering, analyzing and synthesizing scientific evidence related to the therapeutic use of cannabinoids, especially cannabidiol and tetrahydrocannabinol, in patients diagnosed with Autism Spectrum Disorder. This literature review allowed us to consolidate relevant evidence about the therapeutic potential of cannabinoids, especially cannabidiol, as an adjuvant strategy in the management of the symptoms of Autism Spectrum Disorder. The studies analyzed indicate that the use of cannabidiol can contribute to the reduction of symptoms such as irritability, aggression, anxiety and sleep disorders, favoring the adaptive behavior and quality of life of patients with autism spectrum disorder and their caregivers.

COGITOCENTRIC PSYCHOLOGY

Emanuel da Silva Ripardo — 2025-06-03

This study proposes a critical review of the foundations of psychoanalysis, replacing the traditional conception of the unconscious with the notion of Psychic Veiling, a phenomenon responsible for obscuring the affective experience due to excess cognition. It also introduces the concept of Cogitocentrism, understood as the domination of thought over experience, a condition that leads to the alienation of subjectivity. In order to broaden this understanding, the theory of Psyches is presented, understood as dynamic entities that operate between the Implicit Ego and the Explicit Ego, structuring the psyche as a living and continuous flow. Based on contemporary phenomenological and critical reflections, this work proposes paths for a psychology oriented towards the integration of feeling, thinking and existing, offering a renewed perspective on clinical and theoretical processes.

VALPROIC ACID INTERFERENCE IN ABDOMINAL WALL TISSUE REPAIR

Marcos Louro de Hollanda — 2025-06-06

Valproic acid (AVP) is widely used in the treatment of epilepsy and mood disorders, but recent studies suggest that its epigenetic action may negatively interfere in tissue regeneration and healing processes. Repair of the abdominal wall, essential for the success of procedures such as herniorrhaphy and laparotomy, depends on a cascade of inflammatory, cellular and molecular events that can be modulated by systemic drugs such as AVP. The aim of this study was to analyze the interference of valproic acid in abdominal wall healing, considering its possible effects on collagen synthesis, fibroblast proliferation and the integrity of the extracellular matrix, and to discuss its clinical implications in abdominal surgery. This is a literature review with a qualitative and exploratory approach. The studies were selected using the PubMed, SciELO, ScienceDirect and Scopus databases, with full articles published in peer-reviewed scientific journals addressing the use of valproic acid in the context of tissue healing, especially in patients undergoing surgical procedures. The time frame of the research considered the period from 2018 to 2022, based on the oldest article (Costa et al., 2018) and the most recent (Santos et al., 2022; Alves et al., 2022; Moura et al., 2022). The findings indicate that AVP, by acting as a histone deacetylase (HDAC) inhibitor, can alter the gene expression of key proteins in the healing process, such as type I and III collagen, metalloproteinases and growth factors. In experimental models, delayed granulation tissue formation and collagen matrix organization were observed, suggesting an increased risk of dehiscence, incisional hernia and abdominal wall fragility in patients taking the drug continuously. We conclude that valproic acid may represent an underestimated risk factor in surgical repair of the abdominal wall. Preoperative assessment of the use of this drug should be considered in clinical practice, especially in elective surgeries. New clinical studies are needed to validate these experimental findings and guide safer therapeutic approaches.

REMIMAZOLAM VS. PROPOFOL IN SEDATION FOR OUTPATIENT PROCEDURES

João Pedro do Valle Varela — 2025-06-06

Sedation in outpatient procedures requires agents with a favorable pharmacokinetic profile, cardiovascular safety, and rapid recovery. Propofol, traditionally used, is effective but can cause hypotension and respiratory depression. Remimazolam, an ultra-short-acting benzodiazepine, emerges as a promising alternative, combining controllable sedation with an improved safety profile. This study aimed to compare the efficacy, safety, and recovery time of remimazolam versus propofol in patients undergoing outpatient procedures, to assess its clinical feasibility as a substitute or complement to propofol. This is a literature review with a qualitative and exploratory approach. The selection of studies was performed by consulting the PubMed, SciELO, ScienceDirect, and Scopus databases, considering full articles published in peer-reviewed scientific journals that analyze aspects related to the use of remimazolam and propofol in outpatient procedures. The time frame considered publications between 2020 and 2023, based on the oldest articles (da Silva, 2020; Melo, 2020; Rodrigues et al., 2020) and the most recent (Gomes et al., 2023; Carvalho et al., 2023). The data analyzed showed that remimazolam has sedative efficacy comparable to propofol, but with a lower incidence of hypotension, bradycardia, and respiratory depression. In addition, it showed greater predictability in recovery, especially in the elderly and patients with comorbidities. The time to cognitive function recovery and hospital discharge was similar between groups, with a slight advantage for remimazolam in some studies. Its reversibility with flumazenil also offers an additional margin of safety. It is concluded that remimazolam is a safe and effective alternative to propofol for sedation in outpatient procedures, with advantages in specific risk profiles. Despite its higher costs, its use may be preferred in vulnerable populations or in protocols that require rapid recovery and less hemodynamic instability.

EFFECTS OF MEDICINAL BIOMAGNETISM AND DEMAG ON SEVERE DEPRESSION

Claudia Santana de Assis — 2025-06-06

Depression is a prevalent mental disorder invariably accompanied by emotional and physical impairments, as well as limitations in conventional treatment. This study investigated the effects of Magnetic Integrative and Complementary Practices (PICMAG), specifically Medical Biomagnetism (BM) and Magnetic Emotional Dispersion (DEMAG), in managing severe and persistent depression in patients treated at a Psychosocial Care Center (CAPS) within the Brazilian Unified Health System (SUS). The research adopted a mixed-methods approach, combining quantitative and qualitative analyses, involving three participants who underwent eight therapeutic sessions over four weeks. The impact of the interventions was assessed through the WHOQOL-BREF questionnaire and semi-structured interviews. The results indicated a significant improvement in the physical, psychological, and social domains, with a reduction in depressive symptoms, increased vitality, improved sleep quality, and strengthened social interactions, along with notable gains in self-esteem and mood. Qualitative reports reinforced these findings, highlighting emotional relief and the reframing of negative behavioral patterns. Additionally, biomagnetic pairs and destructive mental, behavioral, and attitudinal states (ECADs) were identified suggesting a link between bioenergetic imbalances and depressive symptoms. The analysis suggests that BM and DEMAG may modulate neurochemical and inflammatory activity, promoting emotional stability and symptom relief. Despite limitations such as the small sample size and the absence of a control group, the results point to the potential of these techniques as complementary approaches in mental health care. Future studies with larger samples and neurochemical biomarker monitoring may contribute to validating the efficacy of PICMAG and supporting its incorporation into the Psychosocial Care Network (RAPS) of SUS.