v. 5 n. 06 (2025), Health Studies
v. 5 n. 06 (2025)

SIGNS, SYMPTOMS, AND MECHANISMS IN FIBROMYALGIA: AN EXPERIENCE REPORT AND REVIEW WITH A NEUROSCIENTIFIC FOCUS

Health Studies
Publicado 2025-12-20
Marcelino da Silva Cavalcante
Graduated in Nursing and Obstetrics, Specialist in Neuroscience, Specialist in Anthropology of Health, Master’s student in Cultural Studies.
Jaira Andrade
Nurse, Specialist in Higher Education Teaching
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Palavras-chave

fibromyalgia; chronic pain; central sensitization; neuroscience; fatigue; quality of life.

Como Citar

da Silva Cavalcante, M. ., & Andrade, J. . (2025). SIGNS, SYMPTOMS, AND MECHANISMS IN FIBROMYALGIA: AN EXPERIENCE REPORT AND REVIEW WITH A NEUROSCIENTIFIC FOCUS. Health and Society, 5(06), 176-194. https://doi.org/10.51249/hs.v5i06.2759
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Resumo

This article presents an expanded analysis of the personal report of an individual with fibromyalgia, describing signs and symptoms such as chronic widespread pain, fatigue, sensory hypersensitivity, autonomic changes, and cognitive impairment. The report is integrated with contemporary scientific evidence on neurobiological mechanisms, including central sensitization, nociceptive dysfunction, neurotransmitter dysregulation, autonomic imbalance, and altered brain connectivity. Diagnostic challenges, psychosocial implications, and multidimensional therapeutic strategies are discussed. The text aims to contribute to the dialogue between subjective experience and scientific evidence, reinforcing the biopsychosocial complexity of fibromyalgia.

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Referências

ADLER, S.; et al. Functional Magnetic Resonance Imaging Changes and Increased Muscle Pressure in Fibromyalgia: Insights from Prominent Theories of Pain and Muscle Imaging, preprint, 2023.

ARAÚJO GOMES, M. J. de; FIGUEIREDO, B. Q.; SAINT, B. D.; et al. Possible pathophysiological hypotheses of fibromyalgia. RSD Magazine, v. 11, n. 7, 2022.

ALVAREZ, M. J.; ALBUQUERQUE, M. L. L.; NEIVA, H. P.; CID, L.; TEIXEIRA, D. S.; MATOS, R.; ANTUNES, R.; LUCIO, L.; SANT’ANA, L.; MONTEIRO, D. Understanding the Associations across Fibromyalgia-Related Fatigue, Depression, Anxiety, Self-Esteem Satisfaction with Life and Physical Activity in Portuguese and Brazilian Patients: A Structural Equation Modeling Analysis. Medicine, v. 58, 2022.

HEYMANN, R. E. (Coord.). Brazilian consensus on the treatment of fibromyalgia.Brazilian Journal of Rheumatology, 2010.

OLIVEIRA JÚNIOR, J. O. de; et al. The current treatment of fibromyalgia.Brazilian Journal of Pain (BRJP), 2020.

PONTES-SILVA, A.; et al. Do the instruments used to assess fibromyalgia symptoms according to American College of Rheumatology criteria generate similar scores in other chronic musculoskeletal pain? BMC Musculoskeletal Disorders, 2023.

FREITAS, R. P. de A.; et al. Impacts of social support on symptoms in Brazilian women with fibromyalgia. Journal — (name of the periodical), 2017.

SOUZA, J. B.; et al. The prevalence of fibromyalgia in Brazil – a population-based study. Brazilian Journal of Pain (BRJP) / Pain Magazine, 2018.

WU, G.; TAGLIAZUCCI, E.; CHIALVO, D. R.; MARINAZZO, D. Point-process deconvolution of fMRI reveals effective connectivity alterations in chronic pain patients. arXiv preprint, 2013.

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Copyright (c) 2025 Marcelino da Silva Cavalcante, Jaira Andrade