THE BENEFITS OF NANOSTRUCTURED TRANSDERMAL HORMONAL REPLACEMENT THERAPY IN OROFACIAL HARMOZIZATION TREATMENT
THE BENEFITS (Português (Brasil))

Keywords

bioidentical hormones, testosterone, melatonin, orofacial harmonization rejuvenation.

How to Cite

Maso, A. ., & Tramontini, L. . (2023). THE BENEFITS OF NANOSTRUCTURED TRANSDERMAL HORMONAL REPLACEMENT THERAPY IN OROFACIAL HARMOZIZATION TREATMENT: CASE REPORT. Health and Society, 3(03), 103–124. https://doi.org/10.51249/hs.v3i03.1405

Abstract

The demand for aesthetic and rejuvenating treatments is increasing in society, with that the demand for orofacial harmonization increases exponentially every day. Orofacial harmonization is a set of procedures performed by the Dentist / Dental Surgeon, which aims at the aesthetic and functional balance of the face. Steroid hormones are of great importance in aging due to the decrease of some during this process. However, poor diet including sugar consumption, changes in the sleep cycle, alcohol use, tobacco, lack of exercise and excessive exposure to UV rays also contribute to aging. We present the case of a female patient, 47 years old, who had failures in her menstrual cycle for more than 6 months, and the presence of melasma. Laboratory tests revealed changes in her hormone and vitamin levels, the clinical examination reported dry skin with blemishes, and she also reported excessive fatigue. In order to stabilize melasma and improve the appearance of the skin and obtain a better result in orofacial harmonization, bioidentical steroid hormone replacement therapy and vitamin supplementation were performed. Within 3 months of starting therapy with testosterone, progesterone, melatonin, vitamin D, and supplementation with nutraceuticals, it was observed that during treatment the patient showed a change in the appearance of her skin. The results show that in order to obtain a good response to the orofacilli harmonization treatment, it is extremely important to have a correct homeostasis.

https://doi.org/10.51249/hs.v3i03.1405
THE BENEFITS (Português (Brasil))

References

ANTONIO, C. R. et al. Hormones in rejuvenation: a review of their true effectiveness Surg Cosmet Dermatol 2012;4(4):322-30

ARCANJO D.M , MENEZEZ M.R.S Revista JRG de Estudos Acadêmicos - Ano III (2020), volume III, n.7 (jul./dez.) - ISSN: 2595-1661

Braz, André Vieira Atlas de anatomia e preenchimento global da face/André Vieira Braz, Thais Harumi Sakuma. – 1. ed. – Rio de Janeiro : Guanabara Koogan, 2017. il. ISBN 978-85-277-3248-2

BREDA, P.L.C.L. The benefits of hormonal modulation associated with orofacial harmonization as a means of preventing aging: literature review. Brazilian Journal of Health Review,Brazil, 5n1-317, fev 2022.

BURGER, R.C. Proporção áurea e a harmonização facial. Facsete. 2020. Disponível em: https://faculdadefacsete.edu.br/monografia/items/show/3040. Acesso em: 03.dez. 2021.

COIMBRA DD, URIBE NC, OLIVEIRA BS. “Quadralização facial” no processo do envelhecimento Surg Cosmet Dermatol.2014;6(1):65-71

DE BOER H, BLOK GJ, VAN DER VEEN AE. Clinical aspects of growth hormone deficiency in adults. Endocr Rev. 19

FITZGERALD R, CARQUEVILLE J, YANG PT. Anapproach to structural facial rejuvenation with fillers in women.Int J Womens Dermatol. 2018;5(1):52-67

FUJITA, T.; OHTANI, J.; SHIGEKAWA, M.; et al. Influence of sex hormone disturbances on the internal structure of the mandible in newborn mice. European Journal of Orthodontics, v. 28, n. 2, p. 190–194, 2006.

HANDEL, AC, Miot, LD e Miot, HA (2014a). Melasma: uma revisão clínica e epidemiológica. Dermatol. 89, 771-782.

Kedziora-Kornatowska K, Szewczyk-Golec K, Czuczejko J, Pawluk H, van Marke de Lumen K, Kozakiewicz M, et al. Antioxidative effects of melatonin administration in elderly primary essential hypertension patients. J Pineal Res. 2008;45(3):312-7.

KEMP SF, and FRINDIK JP. Emerging options in growth hormone therapy: an update. Drug Des Devel Ther. 2011;5:411-9.

LEOW,MK, Loh KC. Controversial endocrine interventions for the aged. Singapore Med J. 2006; 47(7):569-79.

LUKACS, John R. Sex differences in dental caries experience: Clinical evidence, complex etiology. Clinical Oral Investigations, v. 15, n. 5, p. 649–656, 2011

LUVIZUTO,Eloá, et al. Arquitetura Facial. 1ª ed.São Paulo: Napoleão Quintessence,2019. 70p.

MARIOTTI, A. (1994) Sex steroid hormones and cell dynamics in the periodontium. Critical Reviews in Oral Biology and Medicine 5, 27– 53.

Muzzalupo R, Tavano L. Entrega niossômica de drogas para direcionamento transdérmico: avanços recentes. Pesquisa e relatórios em entrega transdérmica de medicamentos . 2015;4:23- 33https://doi.org/10.2147/RRTD.S64773.

NOH, TK, Choi, SJ, Chung, BY, Kang, JS, Lee, JH, Lee, MW e Chang, SE (2014). Características inflamatórias das lesões de melasma na pele asiática. J. Dermatol. 41, 788-794.

NOTELOVITZ, Morris. Androgen effects on bone and muscle. Fertility and Sterility, v. 77, n. SUPPL. 4, p. 34–41, 2002.

NUNES, Maria Tereza. Hormônios Tiroideanos: Mecanismo de Ação e Importância Biológica. Arq Bras Endocrinol Metab, [S.I.], v. 6, n. 47, p. 639-643, 02 set. 2003. Disponívelem:https://www.scielo.br/j/abem/a/zntC3gzKybLPfWbbRvWSTZy/? format=pdf&lang=pt. Acesso em: 02 dez. 2021

POROLA, Pauliina. SEX STEROIDS IN SJÖGREN’ S SYNDROME. Acadêmico Dissertation. Intitule of Clinical Medicine, University of Helsinki, Finland.[s.l.: s.n.], 2011.

PEREIRA, F.F (2021) CAMADAS DA FACE E MUDANÇAS ASSOCIADAS COM OENVELHECIMENTO FACIAL Aesthetic Orofacila Science129AOS| Vol. 02 | n. 02| página 129a 143

PEREIRA M.M.Universidade Federal do Rio Grande do Norte Centro de ciências da Saúde,Programa de Pós graduação em ciências Farmacêuticas - 2013

PERLINGEIRO A. Esculpindo Faces Ciência & Arte na Harmonização Orofacial. 1ª ed.São Paulo :Napoleão, 2020 p 89-91

PESSA, JE, Zadoo VP, Mutimer KL, Haffner C, Yuan C, DeWitt AI, Garza JR (2000) Relative maxillary retrusion as a natural consequence of aging: combining skeletal and soft tissue changes into an integratedmodel of midfacial aging. Plast Reconstr Surg102:205–212

RAUTEMAA, Riina; LAUHIO, A.; CULLINAN, M. P.; et al. Oral infections and systemic disease - An emerging problem in medicine. Clinical Microbiology and Infection, v. 13, n. 11, p. 1041–1047, 2007.

RIBEIRO, B.B.; GUERRA, L.M.; GALHARDI, W.M.P.; et al. Importância do Reconhecimento das Manifestações Bucais de Doenças e de Condições Sistêmicas pelos Profissionais de Saúde com Atribuição de Diagnóstico. Odonto, v. 20, n. 39, p. 61–70, 2012.

ROHRICH RJ, AVASHI YJ, Ira L. SAVETSKY IL. Prediction of Facial Aging Using the Facial Fat Compartments. Plast. Reconstr. Surg. 2021; 147: 38S.

ROUGEMONT, Fernanda. Hormônios e o “aprimoramento natural” do corpo: a personalização do processo de envelhecimento na medicina anti-aging. Saúde e Sociedade, São Paulo-Sp, v. 1, n. 29, p. 190-918, ago. 2020.

SILVA , M. K (2020) Atuação da Testosterona estradiol e progesterona na região orofacial

SILVA, Alana Luana Fonseca. Et. al. Uso de esteroides anabolizantes androgênicos e seusefeitos fisiopatológicos. Revista Científica Multidisciplinar Núcleo do Conhecimento. Ano 04, Ed. 03, Vol. 01, pp. 128-151. Março de 2019. ISSN: 2448-0959.

SMALL,Rebeca, et al. Pratical Guide to Dermal Filler Procedures. 1ªed. Rio de Janeiro: DiLivros, 2013. 05p.

SOUZA, A. Guia prático de HRT. Reposição Hormonal e suplementação em Dermatologia Estética. 1ª ed. São Paulo:Napoleão Quintessence.( 2020) p 44

TAICHMAN, L. Susan; HAVENS, Aaron M.; VAN POZNAK, Catherine H. Potential implications of adjuvant endocrine therapy for the oral health of postmenopausal women with breast cancer. Breast Cancer Research and Treatment, v. 137, n. 1, p. 23–32, 2013.

Waterhouse J, Reilly T, Atkinson G, Edwards B. Jet Lag: rends and coping stratefies. Lancet. 2007;369(9587):1117-29.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2023 Adelaide Maso, Luciene Tramontini

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...